Description

NAD+ • 500 mg / vial

Tier One Biosystems – Third-Party Tested | U.S.–Made | Research-Grade

Biological Activity

Nicotinamide adenine dinucleotide (oxidized form, NAD⁺) is a central redox cofactor and signaling metabolite. In cellular systems, NAD⁺ supports mitochondrial energy metabolism (electron transport/oxidative phosphorylation) and serves as a substrate for NAD⁺-consuming enzymes (e.g., sirtuins, PARPs, CD38/CD157), linking it to pathways involved in DNA repair, stress responses, and metabolic regulation.

In Vitro / In Vivo Data

• Widely used in cell and biochemical assays to probe redox state (NAD⁺/NADH), mitochondrial function, and enzyme kinetics of NAD⁺-dependent pathways.

• Common cell-culture working ranges: ~10–1000 µM (protocol-dependent).

• For animal work or specialized protocols, follow your lab’s SOPs and primary literature for solvent, vehicle, and target concentrations.
  (Experimental conditions vary by model; validate in pilot runs.)

Purity & Documentation

• Purity (HPLC): ≥99%

• Independently verified for identity and potency

• COA, SDS, and HPLC/LC-MS data provided for each lot

Molecular Details

Note: Values above correspond to the free-acid form (no counter-ions, no hydration). If a batch is supplied as a salt and/or hydrate, the COA will list the exact formula and molecular weight for that lot.

Physical Properties

Shipping & Handling

Ships at ambient temperature within the U.S. unless otherwise specified. For long-term storage, maintain cold-chain conditions upon receipt.