GHK-Cu
$55.00
50 mg / vial
Third-Party Tested | U.S.–Made | Research-Grade
Out of stock
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Description
Description
GHK-Cu • 50 mg / vial
Tier One Biosystems – Third-Party Tested | U.S.–Made | Research-Grade
Biological Activity
GHK-Cu is the naturally occurring copper(II) complex of the tripeptide Gly-His-Lys (GHK). Literature reports wound-healing, pro-collagen/ECM support, angiogenic, anti-inflammatory, and antioxidant actions across in-vitro and in-vivo models, along with cosmetic studies on aged skin. (These findings pertain to research contexts; not established for clinical use.) PMC+1
In Vivo / In Vitro Data
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Dermal matrix & skin studies: Placebo-controlled cosmetics studies reported increased collagen/skin density and improved photo-aging endpoints after topical GHK-Cu; fibroblast work shows ↑collagen and GAGs at pico- to nanomolar ranges. PMC
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Gene-expression programs: GHK modulates hundreds of genes tied to antioxidant defense, remodeling, and repair (Connectivity Map analyses). PMC+1
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Hair science: Preclinical/clinical-adjacent reports note hair-growth support; newer work suggests synergy with hyaluronic acid on collagen networks relevant to the follicular environment. Wiley Online Library+1
Purity & Documentation
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Purity (HPLC): ≥99%
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Independently verified for identity, potency, and sterility
Molecular Details
| Property | Value |
|---|---|
| Complex / INCI | GHK-Cu (Copper tripeptide-1; Prezatide copper) |
| Peptide Sequence | Gly-His-Lys (GHK) |
| Chemical Formula (complex) | C₁₄H₂₂CuN₆O₄ |
| Average Molecular Weight | ≈ 401.9–402.9 g/mol (vendor/database range) |
| Monoisotopic Mass | ≈ 402.11 Da |
| CAS No. (complex) | 89030-95-5 (GHK peptide alone commonly listed as 49557-75-7) |
Physical Properties
| Property | Specification |
|---|---|
| Appearance | Blue to blue-green lyophilized powder |
| Solubility (in vitro) | Soluble in sterile H₂O or buffered aqueous media; DMSO compatible (use minimal volumes as needed) |
| Storage (sealed) | −20 °C (≥12 mo) or −80 °C (≥24 mo); protect from light & moisture |
| Handling | After reconstitution; avoid repeated freeze–thaw |
Shipping & Handling
Ships at ambient temperature within the U.S. unless otherwise specified. Maintain cold-chain for long-term storage after receipt.
References
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Pickart L. The human tripeptide GHK-Cu: antioxidant, anti-inflammatory, regenerative & wound-healing actions (review). Oxid Med Cell Longev. 2012. PMC
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Pickart L. GHK as a natural modulator of multiple cellular pathways; clinical cosmetics data on skin density/wrinkles. J Biomater Tissue Eng. 2015 (PMC review). PMC
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Pickart L. GHK and gene expression (Connectivity Map analyses). BioMed Res Int. 2017. PMC
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Jiang F. Synergy of GHK-Cu and hyaluronic acid on collagen I/IV/VII (cosmetic derm). J Cosmet Dermatol. 2023. Wiley Online Library
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DrugBank / FDA G-SRS. Prezatide copper (GHK-Cu) identifiers, formula, and masses. DrugBank+1
Research Use Only – Not for Human Consumption
Supplied exclusively for laboratory research, analytical testing, and scientific investigation.
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